Apixaban-d3
Names
Biological Activity
[Description]:
Apixaban-d3 (BMS-562247-01-d3)is the deuterium labeledApixaban(HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C25H22D3N5O4
[ Molecular Weight ]:
462.52
[ Exact Mass ]:
462.20900
[ PSA ]:
111.75000
[ LogP ]:
3.71380