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Ac-IEPD-AFC

Names

[ CAS No. ]:
1135417-31-0

[ Name ]:
Ac-IEPD-AFC

[Synonym ]:
L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-α-asparagine

Biological Activity

[Description]:

Ac-IEPD-AFC (IEPD) is a substrate of Granzyme B[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

The Km of human granzyme B for Ac-IEPD-AFC in granzyme B assay buffer is 585 μM[1].

[References]

[1]. Pak SC, et al. SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. J Biol Chem. 2004 Apr 9;279(15):15448-59.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1073.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H38F3N5O11

[ Molecular Weight ]:
725.67

[ Flash Point ]:
603.3±34.3 °C

[ Exact Mass ]:
725.252014

[ LogP ]:
2.49

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.575

Related Compounds