Neuropeptide Y (13-36) (porcine) trifluoroacetate salt

Names

[ CAS No. ]:
113662-54-7

[ Name ]:
Neuropeptide Y (13-36) (porcine) trifluoroacetate salt

[Synonym ]:
npy 13-36
PAEDLARYYSALRHYINLITRQRY-NH2

Biological Activity

[Description]:

Neuropeptide Y (13-36), porcine is a selective neuropeptide Y2 receptor agonist[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor

[References]

[1]. Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃₅H₂₀₉N₄₁O₃₆

[ Molecular Weight ]:
2982.36000

[ Exact Mass ]:
2980.58000

[ PSA ]:
1282.86000

[ LogP ]:
5.51400

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Regulation of neuropeptide Y release by neuropeptide Y receptor ligands and calcium channel antagonists in hypothalamic slices.

J. Neurochem. 73 , 641-646, (1999)

Neuropeptide Y (NPY) is an important regulator of energy balance in mammals through its orexigenic, antithermogenic, and insulin secretagogue actions. We investigated the regulation of endogenous NPY ...

Neuropeptide Y produces anxiety via Y2-type receptors.

Peptides 19 , 359-363, (1998)

In the present study, the effects of intracerebroventricular (ICV) NPY, [Leu31, Pro34]NPY and NPY13-36 have been evaluated with respect to anxiety in mice in the elevated plus maze. NPY had opposing e...

Evidence for Y1 and Y2 subtypes of neuropeptide Y receptors linked to opposing postjunctional effects observed in rat cardiac myocytes.

Eur. J. Pharmacol. 336 , 257, (1997)

The aim of this study was to confirm the existence of and identify the receptor subtypes for neuropeptide Y that are present post-junctionally in myocardium. The effects of the selective agonists, [Le...