Fura 2 pentapotassium salt

Names

[ Name ]:
Fura 2 pentapotassium salt

[Synonym ]:
FURA 2 PENTAPOTASSIUM SALT
Fura-2,pentapotassium salt
MFCD00083328

Biological Activity

[Description]:

Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Fura-2 pentapotassium (10 μM, 2 min) can be used to detect changes in the concentration of calcium ions in neutrophils of heparinized peripheral blood[1]. Fura-2 pentapotassium (10 μM, 5 min) can be used as a calcium probe to assess the distribution of calcium ions within heart mitochondria without affecting the activity of it in rat[2].

[References]

[1]. Omar Rafael Alemán, et al. The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. Front Immunol. 2021 May 13;12:657393. doi: 10.3389/fimmu.2021.657393.

[2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7.

Chemical & Physical Properties

[ Boiling Point ]:
983.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₉H₂₂K₅N₃O₁₄

[ Molecular Weight ]:
831.98800

[ Flash Point ]:
548.6ºC

[ Exact Mass ]:
830.92900

[ PSA ]:
264.76000

[ Vapour Pressure ]:
0mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport