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Mal-amido-PEG10-C2-​NHS ester

Names

[ CAS No. ]:
1137109-22-8

[ Name ]:
Mal-amido-PEG10-C2-​NHS ester

[Synonym ]:
α-Maleimidopropionyl-ω-succinimidyl-10(ethylene glycol)

Biological Activity

[Description]:

Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Noncleavable


[References]

[1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.

[2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A

Chemical & Physical Properties

[ Molecular Formula ]:
C34H55N3O17

[ Molecular Weight ]:
777.81000

[ Exact Mass ]:
777.35300

[ PSA ]:
222.46000

Related Compounds