Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride

Names

[ Name ]:
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride

[Synonym ]:
tert-butyl N-[5-amino-1-[[1-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]carbamate

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₂N₈O₈

[ Molecular Weight ]:
630.69300

[ Exact Mass ]:
630.31300

[ PSA ]:
260.83000

[ LogP ]:
3.58840

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin.

Eur. J. Biochem. 172 , 17, (1988)

Seventy-four peptide amides of 7-amino-4-methylcoumarin (Mec) of the type Boc-Xaa-Yaa-Arg-NH-Mec were newly synthesized and tested to find specific substrates for blood-clotting proteases and trypsin....

Discovery of indole tetrafluorophenoxymethylketone-based potent novel small molecule inhibitors of caspase-3.

Org. Med. Chem. Lett. 2 , 27, (2012)

Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a therapeutic target has led many to pursue the devel...