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7-epi-Isogarcinol

Names

[ CAS No. ]:
1141378-40-6

[ Name ]:
7-epi-Isogarcinol

Biological Activity

[Description]:

7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> STAT
Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> STAT

[Target]

STAT3


[References]

[1]. Xu ZH, et al. Polycyclic Polyprenylated Acylphloroglucinols Bearing a Lavandulyl-Derived Substituent from Garcinia xanthochymus Fruits. J Nat Prod. 2022 Dec 23;85(12):2845-2855.  

Chemical & Physical Properties

[ Molecular Formula ]:
C38H50O6

[ Molecular Weight ]:
602.80

Related Compounds