6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester

Names

[ Name ]:
6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester

[Synonym ]:
6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester
5(6)-SFX [6-(Fluorescein-5(6)-carboxamido)hexanoic acid,succinimidyl ester]
FLUORESCEIN-5(6)-CARBOXAMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER

Biological Activity

[Description]:

5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kenneth J, et al. Methods For The Detection, Analysis And Isolation Of Nascent Proteins. US20110250609.

[2]. Ito K, et al. Artificial human Met agonists based on macrocycle scaffolds. Nat Commun. 2015 Mar 11;6:6373.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₂₆N₂O₁₀

[ Molecular Weight ]:
586.54600

[ Exact Mass ]:
586.15900

[ PSA ]:
168.77000

[ LogP ]:
3.89200

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease.

Autophagy 11(2) , 385-402, (2015)

Mitochondria-induced oxidative stress and flawed autophagy are common features of neurodegenerative and lysosomal storage diseases (LSDs). Although defective autophagy is particularly prominent in Pom...

Liver cell uptake and degradation of soluble immunoglobulin G immune complexes in vivo and in vitro in rats.

Hepatology 24 , 169-175, (1996)

Immune complexes were formed between dinitrophenylated human serum albumin (DNP-HSA) and polyclonal rabbit immunoglobulin G (IgG) anti-DNP antibodies at antibody excess. The antigen was labelled with ...

Dynamics at Lys-553 of the acto-myosin interface in the weakly and strongly bound states.

Biophys. J. 78 , 1441-1448, (2000)

Lys-553 of skeletal muscle myosin subfragment 1 (S1) was specifically labeled with the fluorescent probe FHS (6-[fluorescein-5(and 6)-carboxamido]hexanoic acid succinimidyl ester) and fluorescence que...