MK-3901
Names
[ CAS No. ]:
1149750-69-5
[ Name ]:
MK-3901
Biological Activity
[Description]:
MK-3901 is a potent, selective, orally active P2X3 antagonist with IC50 of 21 nM; demonstrates efficacy similar to that of naproxen, after 60 mg/kg (p.o.) administration with EC90 of approximately 3 uM in the rat CFA model of inflammatory pain.
[References]
References 1. Ginnetti AT, et al. Bioorg Med Chem Lett. 2018 May 1;28(8):1392-1396. View Related Products by Target P2X Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C28H24FN5O2
[ Molecular Weight ]:
481.531