thebaine
Controlled Substances
Names
[ CAS No. ]:
115-37-7
[ Name ]:
thebaine
[Synonym ]:
3-O-Methyl-oripavin
THEBAINE
Thebain
(4R,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline
4,5alpha-Epoxy-3,6-dimethoxy-17-methyl-6,8-morphinadien
MFCD00027409
Paramorphine
DEA No. 9333
EINECS 204-084-1
Chemical & Physical Properties
[ Density]:
1.3g/cm3
[ Boiling Point ]:
467.6ºC at 760mmHg
[ Melting Point ]:
183-186ºC (dec.)
[ Molecular Formula ]:
C19H21NO3
[ Molecular Weight ]:
311.37500
[ Flash Point ]:
141ºC
[ Exact Mass ]:
311.15200
[ PSA ]:
30.93000
[ LogP ]:
2.36240
[ Vapour Pressure ]:
6.4E-09mmHg at 25°C
[ Index of Refraction ]:
1.648
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD2975000
- CHEMICAL NAME :
- Morphinan, 6,7,8,14-tetradehydro-4,5-alpha-epoxy-3,6-dimethoxy-1 7-methyl-
- CAS REGISTRY NUMBER :
- 115-37-7
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H21-N-O3
- MOLECULAR WEIGHT :
- 311.41
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX HO PN GH&&&TTJ FO1 JO1 P1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 114 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (4),20,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 54 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (4),20,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 6,755,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 31 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,31,1938
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H310-H330
[ Precautionary Statements ]:
P260-P280-P284-P301 + P310-P302 + P350-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
26/27/28
[ Safety Phrases ]:
S22;S45;S36/S37/S39
[ RIDADR ]:
UN 1544 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
QD2975000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)