caulophine

Names

[ Name ]:
caulophine

[Synonym ]:
3-[2-(Dimethylamino)ethyl]-4,5-dihydroxy-1,6-dimethoxy-9H-fluoren-9-one
9H-Fluoren-9-one, 3-[2-(dimethylamino)ethyl]-4,5-dihydroxy-1,6-dimethoxy-
caulophine

Biological Activity

[Description]:

Caulophine is a fluoroketone alkaloid isolated from Caulophyllum robustum MAXIM. Caulophine has antioxidant activity and the ability to protect cardiomyocytes from oxidative and ischemic damage, providing potential value for coronary heart disease research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Kaiwei Si, et al. Caulophine protects cardiomyocytes from oxidative and ischemic injury. J Pharmacol Sci. 2010;113(4):368-77.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
576.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₁NO₅

[ Molecular Weight ]:
343.374

[ Flash Point ]:
302.2±30.1 °C

[ Exact Mass ]:
343.141968

[ LogP ]:
2.35

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.631