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RETF-4NA TFA

Names

[ CAS No. ]:
1160928-63-1

[ Name ]:
RETF-4NA TFA

Biological Activity

[Description]:

RETF-4NA, a chymase-specific substrate, is a sensitive and selective substrate for chymase when free or bound to α2M[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Wilfred W Raymond, et al. Alpha 2-macroglobulin Capture Allows Detection of Mast Cell Chymase in Serum and Creates a Reservoir of Angiotensin II-generating Activity. J Immunol. 2009 May 1;182(9):5770-7.

[2]. Katariina Maaninka, et al. Human Mast Cells Arise From a Common Circulating Progenitor. J Allergy Clin Immunol. 2013 Aug;132(2):463-9.e3.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₄₃N₉O₁₀

[ Molecular Weight ]:
713.73800

[ Exact Mass ]:
713.31300

[ PSA ]:
324.71000

[ LogP ]:
4.39230

Related Compounds