LYG-202

Names

[ Name ]:
LYG-202

[Synonym ]:
lyg-202

Biological Activity

[Description]:

LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. LYG-202 inhibits VEGF-stimulated HUVEC migration and tube formation. LYG-202 induces cancer cell apoptosis[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Chen Y, et al. LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. J Pharmacol Sci. 2010;112(1):37-45.

[2]. Zhao Y, et al. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells. Apoptosis. 2015 Sep;20(9):1253-69.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₀N₂O₅

[ Molecular Weight ]:
438.51600

[ Exact Mass ]:
438.21500

[ PSA ]:
75.38000

[ LogP ]:
3.45640

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

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To maintain genome stability, the thousands of replication origins of mammalian genomes must only initiate replication once per cell cycle. This is achieved by a strict temporal separation of ongoing ...