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(Rac)-Zearalenone-d6

Names

[ CAS No. ]:
1185236-04-7

[ Name ]:
(Rac)-Zearalenone-d6

[Synonym ]:
(11E)-14,16-Dihydroxy-3-(<sup>2</sup>H<sub>3</sub>)methyl(3,4,4-<sup>2</sup>H<sub>3</sub>)-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione

Biological Activity

[Description]:

(Rac)-Zearalenone-d6 is the deuterium labled Zearalenone (HY-103447). Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Zinedine A, et al. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin. Food Chem Toxicol. 2007 Jan;45(1):1-18.  

[2]. Richard JL, et al. Some major mycotoxins and their mycotoxicoses--an overview. Int J Food Microbiol. 2007 Oct 20;119(1-2):3-10.  

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H16D6O5

[ Molecular Weight ]:
324.40

[ Exact Mass ]:
324.18400

[ PSA ]:
83.83000

[ LogP ]:
3.57960

Related Compounds