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Emtricitabine triphosphate tetrasodium salt

Names

[ CAS No. ]:
1188407-46-6

[ Name ]:
Emtricitabine triphosphate tetrasodium salt

Biological Activity

[Description]:

Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> HBV
Signaling Pathways >> Anti-infection >> Reverse Transcriptase

[References]

[1]. Frasca K, et al. Emtricitabine triphosphate in dried blood spots is a predictor of viral suppression in HIV infection and reflects short-term adherence to antiretroviral therapy. J Antimicrob Chemother. 2019 May 1;74(5):1395-1401.  

[2]. Bang LM, et al. Emtricitabine: an antiretroviral agent for HIV infection. Drugs. 2003;63(22):2413-24; discussion 2425-6.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H9FN3Na4O12P3S

Related Compounds