Erlotinib-d6 (hydrochloride)

Names

[ Name ]:
Erlotinib-d6 (hydrochloride)

[Synonym ]:
Erlotinib Impurity 38

Biological Activity

[Description]:

Erlotinib D6 hydrochloride (CP-358774 D6 hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an 50 of 2 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

Signaling Pathways >> Autophagy >> Autophagy

[References]

[1]. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₈D₆ClN₃O₄

[ Molecular Weight ]:
435.93400

[ Exact Mass ]:
435.18300

[ PSA ]:
74.73000

[ LogP ]:
4.28010

[ Storage condition ]:
-20°C

Erlotinib-d6 (hydrochloride)

Names

Biological Activity

Chemical & Physical Properties

Related Compounds