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Trimethoprim-13C3

Names

[ CAS No. ]:
1189970-95-3

[ Name ]:
Trimethoprim-13C3

[Synonym ]:
5-[[3,4,5-tri(methoxy)phenyl]methyl]pyrimidine-2,4-diamine

Biological Activity

[Description]:

Trimethoprim-13C3is the deuterium labeledTrimethoprim(HY-B0510)[1]. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[2][3][4][5].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C1113C3H18N4O3

[ Molecular Weight ]:
293.30

[ Exact Mass ]:
293.14800

[ PSA ]:
106.97000

[ LogP ]:
1.11780

Related Compounds