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(2H14)Nonanedioic acid

Names

[ CAS No. ]:
119176-67-9

[ Name ]:
(2H14)Nonanedioic acid

[Synonym ]:
Nonanedioic-D14 Acid
(H)Nonanedioic acid
Nonanedioic-d acid

Biological Activity

[Description]:

Azelaic acid-d14 is the deuterium labeled Azelaic acid[1]. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners[2][3].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324(5923):89-91.  

[3]. Liu RH, et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. Arch Dermatol. 2006 Aug142(8):1047-52.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
370.5±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H2D14O4

[ Molecular Weight ]:
202.307

[ Flash Point ]:
192.1±19.7 °C

[ Exact Mass ]:
202.192734

[ PSA ]:
74.60000

[ LogP ]:
1.33

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.475

Related Compounds