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sulfo-SPDB

Names

[ CAS No. ]:
1193111-39-5

[ Name ]:
sulfo-SPDB

[Synonym ]:
MFCD20227457

Biological Activity

[Description]:

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H14N2O7S3

[ Molecular Weight ]:
406.45

[ Storage condition ]:
2-8°C


Related Compounds