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U-75302

Names

[ CAS No. ]:
119477-85-9

[ Name ]:
U-75302

[Synonym ]:
1,5-Hexanediol, 6-[6-[(1E,3R,5Z)-3-hydroxy-1,5-undecadien-1-yl]-2-pyridinyl]-, (5S)-
(5S)-6-{6-[(1E,3R,5Z)-3-Hydroxy-1,5-undecadien-1-yl]-2-pyridinyl}-1,5-hexanediol

Biological Activity

[Description]:

U-75302 is a potent inhibitor of leukotriene B4. U-75302 is a pyridine analogue. U-75302 has the potential for the research of inflammatory diseases[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor
Research Areas >> Inflammation/Immunology

[References]

[1]. Lin AH, et al. Novel molecules that antagonize leukotriene B4 binding to neutrophils. Ann N Y Acad Sci. 1988;524:196-200.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
567.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H35NO3

[ Molecular Weight ]:
361.52

[ Flash Point ]:
296.8±30.1 °C

[ Exact Mass ]:
361.261688

[ PSA ]:
73.58000

[ LogP ]:
3.05

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.557

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

Related Compounds