Propargyl-PEG8-NH2

Names

[ CAS No. ]:
1196732-52-1

[ Name ]:
Propargyl-PEG8-NH2

[Synonym ]:
3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine

[Description]:

Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
477.4±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₃₇NO₈

[ Molecular Weight ]:
407.499

[ Flash Point ]:
232.8±21.0 °C

[ Exact Mass ]:
407.251923

[ LogP ]:
-2.61

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.466

[ Hazard Codes ]:
Xi