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GPR4 antagonist 1

Names

[ CAS No. ]:
1197879-16-5

[ Name ]:
GPR4 antagonist 1

[Synonym ]:
2-Ethyl-3-{4-[(E)-3-(4-isopropyl-piperazin-1-yl)-propenyl]-benzyl}-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
GPR4 RECEPTOR MODULATOR 46

Biological Activity

[Description]:

GPR4 antagonist 1 is a GPR4 antagonist, with an IC50 of 189 nM.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[Target]

IC50: 189 nM (GPR4)[1].


[References]

[1]. ARYL SULFONOHYDRAZIDES. US 20090291942 A1.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C27H37N5

[ Molecular Weight ]:
431.61600

[ Exact Mass ]:
431.30500

[ PSA ]:
37.19000

[ LogP ]:
4.57380


Related Compounds