S07-2001

Names

[ CAS No. ]:
1197904-57-6

[ Name ]:
S07-2001

Biological Activity

[Description]:

S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

S07-2001 (50 μM) reduces 27% of MCF-7 cell viability administrated with Doxorubicin[1].


[References]

[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H17N3O4S

[ Molecular Weight ]:
335.38

Related Compounds