β-catenin/CBP-IN-1

Names

[ CAS No. ]:
1198780-38-9

[ Name ]:
β-catenin/CBP-IN-1

Biological Activity

[Description]:

β-catenin/CBP-IN-1 (CBP/β-catenin inhibitor) is a potent and selective CBP/β-catenin inhibitor, extracted from the patent WO2014092154A1. β-catenin/CBP-IN-1 has the potential for the study of liver fibrosis induced by hepatitis virus[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> Wnt
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

Wnt


[In Vivo]

β-catenin/CBP-IN-1 (intraperitoneal injection;1mg/kg; 42 days) has a treatment effect on liver fibrosis in hepatic fibrosis Cre/loxP/HCV-MxCreTg mouse model[1].

[References]

[1]. Takenao Odagami, et al. Prevention or treatment agent for hepatic fibrosis. Patent WO2014092154A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H35N6O7P

[ Molecular Weight ]:
658.64

Related Compounds