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Omeprazole Acid Disodium Salt

Names

[ CAS No. ]:
120003-84-1

[ Name ]:
Omeprazole Acid Disodium Salt

[Synonym ]:
3-Pyridinecarboxylic acid, 4-methoxy-6-[[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-, sodium salt (1:2)
Disodium 4-methoxy-6-{[(5-methoxybenzimidazol-1-id-2-yl)sulfinyl]methyl}-5-methylnicotinate

Chemical & Physical Properties

[ Melting Point ]:
>300° C (dec.)

[ Molecular Formula ]:
C17H15N3Na2O5S

[ Molecular Weight ]:
419.36

[ Exact Mass ]:
419.052795

[ Water Solubility ]:
Soluble in methanol, and water.

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Identification of two main urinary metabolites of [14C]omeprazole in humans.

Drug Metab. Dispos. 17(1) , 69-76, (1989)

The excretion and metabolism of [14C]omeprazole given orally as a suspension was studied in 10 healthy male subjects. An average of 79% of the dose was recovered in the urine in 96 hr, with most of th...

Development and preliminary application of a high-performance liquid chromatographic assay for omeprazole metabolism in human liver microsomes.

J. Pharm. Biomed. Anal. 12(6) , 839-44, (1994)

A high-performance liquid chromatography assay was developed to measure the enzymatic activities of the 5-hydroxylation and sulphoxidation of omeprazole, a proton pump inhibitor, in human liver micros...


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