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AZD-8165

Names

[ CAS No. ]:
1201686-72-7

[ Name ]:
AZD-8165

[Synonym ]:
AZD8165
1H-Pyrazole-5-carboximidic acid, N-[[5-chloro-2-(1H-tetrazol-1-yl)phenyl]methyl]-1-[(2R)-2-(4-fluorophenyl)-2-(1-oxopropoxy)acetyl]-4,5-dihydro-, (5S)-
7WO8I5IY24
(5S)-N-[5-Chloro-2-(1H-tetrazol-1-yl)benzyl]-1-[(2R)-2-(4-fluorophenyl)-2-(propionyloxy)acetyl]-4,5-dihydro-1H-pyrazole-5-carboximidic acid

Biological Activity

[Description]:

AZD-8165 is a potent, selective and oral thrombin inhibitor for treatment of thrombosis. Thrombosis Phase 1 Discontinued

[References]

References View Related Products by Target Thrombin Thrombosis

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
706.7±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H21ClFN7O4

[ Molecular Weight ]:
513.909

[ Flash Point ]:
381.2±35.7 °C

[ Exact Mass ]:
513.132751

[ LogP ]:
2.19

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.681

Related Compounds