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4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan

Names

[ CAS No. ]:
1206464-65-4

[ Name ]:
4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan

[Synonym ]:
4,4'-{[(2S,3S,4S)-2-Methoxytetrahydrofuran-3,4-diyl]bis(methylene)}bis(2-methoxyphenol)
Phenol, 4,4'-[[(2S,3S,4S)-tetrahydro-2-methoxy-3,4-furandiyl]bis(methylene)]bis[2-methoxy-

Biological Activity

[Description]:

4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC50s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Li H, et al. Cytotoxic lignans from Viburnum foetidum. Arch Pharm Res. 2013 Oct;36(10):1211-4.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
545.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H26O6

[ Molecular Weight ]:
374.43

[ Flash Point ]:
283.7±30.1 °C

[ Exact Mass ]:
374.172943

[ PSA ]:
77.38000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.594

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds