5-(N,N-Dimethyl)amiloride hydrochloride

Names

[ Name ]:
5-(N,N-Dimethyl)amiloride hydrochloride

[Synonym ]:
5-dimethylamiloride
DMA HYDROCHLORIDE
N-amidino-3-amino-5-dimethylamino-6-chloro-2-pyrazinecarboxamide
3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide
AMILORIDE,5-(N,N-DIMETHYL)-,HYDROCHLORIDE
5-N-dimethyl amiloride
5-(N,N-dimethyl)-amiloride
3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide
3-amino-6-chloro-5-dimethylamino-pyrazine-2-carboxylic acid carbamimidoylamide
dimethyl amiloride
6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide
5-(N,N-DIMETHYL)AMILORIDE HCL
MFCD00069207

Biological Activity

[Description]:

Dimethylamiloride is a specific antiporter inhibitor[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

Antiporter[1]

[References]

[1]. Vilella S, et al. Angiotensin II stimulation of the basolateral located Na+/H+ antiporter in eel (Anguilla anguilla) enterocytes. J Mol Endocrinol. 1996 Feb;16(1):57-62.

Chemical & Physical Properties

[ Density]:
1.68g/cm3

[ Boiling Point ]:
543.6ºC at 760mmHg

[ Melting Point ]:
216-217°C(lit.)

[ Molecular Formula ]:
C₈H₁₂ClN₇O

[ Molecular Weight ]:
257.68

[ Flash Point ]:
282.5ºC

[ Exact Mass ]:
293.05600

[ PSA ]:
136.51000

[ LogP ]:
1.97560

[ Vapour Pressure ]:
7.08E-12mmHg at 25°C

[ Index of Refraction ]:
1.725

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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