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Azido-PEG8-acid

Names

[ CAS No. ]:
1214319-92-2

[ Name ]:
Azido-PEG8-acid

[Synonym ]:
N3-PEG8-CH2CH2COOH

Biological Activity

[Description]:

Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Tan M, et al. Peptide-targeted Nanoglobular Gd-DOTA monoamide conjugates for magnetic resonance cancer molecular imaging. Biomacromolecules. 2010 Mar 8;11(3):754-61.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H37N3O10

[ Molecular Weight ]:
467.51118

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds