B-Raf IN 8
Names
[ CAS No. ]:
1215313-19-1
[ Name ]:
B-Raf IN 8
Biological Activity
[Description]:
B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM[1].
[Related Catalog]:
[Target]
B-Raf:70.65 ± 0. nM (IC50)
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H17N3O2
[ Molecular Weight ]:
307.35