Deet-d10

Names

[ Name ]:
Deet-d10

[Synonym ]:
DEET-d10
N,N-(Diethyl-d10)-3-methylbenzamide (N,N-(Diethyl-d10)-m-toluamide
3-Methyl-N,N-(diethyl-d10)benzamide
Flypel-d10
m-Delphene-d10
M-Det-d10
m-DETA-d10
N,N-(Diethyl-d10)-m-toluamide
Metadelphene-d10
Dieltamid-d10

Biological Activity

[Description]:

Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide[1]. Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects[2].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Lu W, et al. DEET as a feeding deterrent. PLoS One. 2017 Dec 14;12(12):e0189243.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₇D₁₀NO

[ Molecular Weight ]:
201.33100

[ Exact Mass ]:
201.19400

[ PSA ]:
20.31000

[ LogP ]:
2.47700

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H412

[ Precautionary Statements ]:
P273-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport