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(Rac)-Mirabegron D5

Names

[ CAS No. ]:
1215807-38-7

[ Name ]:
(Rac)-Mirabegron D5

[Synonym ]:
4-Thiazoleacetamide, 2-amino-N-[4-[2-[[2-hydroxy-2-(phenyl-d5)ethyl]amino]ethyl]phenyl]-
2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[2-hydroxy-2-(2H5)phenylethyl]amino}ethyl)phenyl]acetamide

Biological Activity

[Description]:

(Rac)-Mirabegron D5 ((Rac)-YM178 D5) is a deuterium labeled (Rac)-Mirabegron. (Rac)-Mirabegron is the racemate of Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[References]

[1]. Takasu T, et al. Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321(2):642-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
690.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H19D5N4O2S

[ Molecular Weight ]:
401.537

[ Flash Point ]:
371.1±31.5 °C

[ Exact Mass ]:
401.193390

[ LogP ]:
1.29

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.681

Related Compounds