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BYK 191023 dihydrochloride

Names

[ CAS No. ]:
1216722-25-6

[ Name ]:
BYK 191023 dihydrochloride

[Synonym ]:
1H-Imidazo[4,5-b]pyridine, 2-[2-(4-methoxy-2-pyridinyl)ethyl]-, hydrochloride (1:2)
2-[2-(4-Methoxypyridin-2-yl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride
2-[2-(4-Methoxy-2-pyridinyl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride

Biological Activity

[Description]:

BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Tiso M, et al. BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase. Mol Pharmacol. 2008 Apr;73(4):1244-53.  

Chemical & Physical Properties

[ Molecular Formula ]:
C14H16Cl2N4O

[ Molecular Weight ]:
327.21

[ Exact Mass ]:
326.070129

[ Storage condition ]:
Store at -20℃

[ Water Solubility ]:
Soluble in H2O

Related Compounds