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Fmoc-Ile-OH-13C6,15N

Names

[ CAS No. ]:
1217442-29-9

[ Name ]:
Fmoc-Ile-OH-13C6,15N

[Synonym ]:
N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine-¹³C₆,¹⁵N, L-Isoleucine-¹³C₆,¹⁵N, N-Fmoc, ¹³C and ¹⁵N Labeled Fmoc-Ile-OH
MFCD06798062

Biological Activity

[Description]:

Fmoc-Ile-OH-13C6,15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Melting Point ]:
145-147℃ (lit.)

[ Molecular Formula ]:
13CH313CH213CH(13CH3)13CH(15NH-Fmoc)13CO2H

[ Molecular Weight ]:
360.36

[ Exact Mass ]:
360.179871

[ Index of Refraction ]:
1.583


Related Compounds