L-Lysine6-13C dihydrochloride

Names

[ CAS No. ]:
1217466-44-8

[ Name ]:
L-Lysine6-13C dihydrochloride

[Synonym ]:
L-Lysine-6-13C dihydrochloride

Biological Activity

[Description]:

L-Lysine6-13C (dihydrochloride) is a 13C-labeled Sulfamethoxypyridazine.

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-229.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-229.

Chemical & Physical Properties

[ Molecular Formula ]:
C513CH16Cl2N2O2

[ Molecular Weight ]:
220.10

[ Exact Mass ]:
219.06200

[ PSA ]:
89.34000

[ LogP ]:
2.53190

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Related Compounds