Lubiprostone-d7

Names

[ CAS No. ]:
1217675-13-2

[ Name ]:
Lubiprostone-d7

Biological Activity

[Description]:

Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. http://en.wikipedia.org/wiki/Lubiprostone

Chemical & Physical Properties

[ Molecular Formula ]:
C20H25D7F2O5

[ Molecular Weight ]:
397.51

Related Compounds