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Repaglinide D5

Names

[ CAS No. ]:
1217709-85-7

[ Name ]:
Repaglinide D5

[Synonym ]:
[2H5]-Repaglinide
Repaglinide-ethyl-d5

Biological Activity

[Description]:

Repaglinide D5 (AG-EE 623ZW D5) is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[In Vitro]

Repaglinide reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted[1].

[References]

[1]. Wang LC, et al. Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus.Medicine (Baltimore). 2018 Sep;97(38):e12476.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H31D5N2O4

[ Molecular Weight ]:
457.61700

[ Exact Mass ]:
457.29900

[ PSA ]:
82.36000

[ LogP ]:
6.12520

[ Storage condition ]:
-20°C

Related Compounds