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Thyroxine-13C6

Names

[ CAS No. ]:
1217780-14-7

[ Name ]:
Thyroxine-13C6

Biological Activity

[Description]:

L-Thyroxine-13C6-1 (Levothyroxine-13C6-1; T4-13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1][2].

[Related Catalog]:

Research Areas >> Endocrinology

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.  

[2]. Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323.  

[3]. Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149.  

Chemical & Physical Properties

[ Molecular Formula ]:
C913C6H11I4NO4

[ Molecular Weight ]:
782.83

Related Compounds