2-[(Difluoromethyl)sulfonyl]pyridine
Names
[ CAS No. ]:
1219454-89-3
[ Name ]:
2-[(Difluoromethyl)sulfonyl]pyridine
[Synonym ]:
Difluoromethyl 2-pyridyl sulfone
2-[(Difluoromethyl)sulfonyl]pyridine
Pyridine, 2-[(difluoromethyl)sulfonyl]-
2-(difluoromethylsulfonyl)pyridine
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
324.4±42.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H5F2NO2S
[ Molecular Weight ]:
193.171
[ Flash Point ]:
150.0±27.9 °C
[ Exact Mass ]:
193.000900
[ PSA ]:
55.41000
[ LogP ]:
0.38
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.475
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H319
[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338
[ Hazard Codes ]:
Xn
[ RIDADR ]:
UN 2811 6.1 / PGIII
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Angew. Chem. Int. Ed. Engl. 52 , 3949-3952, (2013)
Difluoromethyl 2-pyridyl sulfone: a new gem-difluoroolefination reagent for aldehydes and ketones.
Org. Lett. 12 , 1444-1447, (2010)
Difluoromethyl 2-pyridyl sulfone, a previously unknown compound, was found to act as a novel and efficient gem-difluoroolefination reagent for both aldehydes and ketones. It was found that the fluorin...
From difluoromethyl 2-pyridyl sulfone to difluorinated sulfonates: a protocol for nucleophilic difluoro(sulfonato)methylation.Angew. Chem. Int. Ed. Engl. 50 , 2559-2563, (2011)