AMPK activator 991

Names

[ CAS No. ]:
1219739-95-3

[ Name ]:
AMPK activator 991

Biological Activity

[Description]:

AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.

[References]

References 1. Willows R, et al. Biochem J. 2017 Aug 22;474(17):3059-3073. 2. Ngoei KRW, et al. Cell Chem Biol. 2018 Jun 21;25(6):728-737.e9. View Related Products by Target AMPK

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₁₈ClN₃O₃

[ Molecular Weight ]:
431.876

Related Compounds

AMPK activator 4
AMPK activator D942
AMPK activator 9
AMPK activator 10
AMPK activator 1
AMPK activator 7
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
2-[5-(cyclopropylmethyl)-1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]ethan-1-amine
(3R)-1-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]acetyl}piperidine-3-carboxylic acid
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine