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Hexazinone-d6

Names

[ CAS No. ]:
1219804-22-4

[ Name ]:
Hexazinone-d6

[Synonym ]:
6-{Bis[(H)methyl]amino}-3-cyclohexyl-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
1,3,5-Triazine-2,4(1H,3H)-dione, 3-cyclohexyl-6-(dimethyl-d-amino)-1-methyl-

Biological Activity

[Description]:

Hexazinone-d6 is the deuterium labeled Hexazinone[1]. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Hexazinone.From Wikipedia

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
332.8±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H14D6N4O2

[ Molecular Weight ]:
258.350

[ Flash Point ]:
155.1±23.2 °C

[ Exact Mass ]:
258.196289

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.612


Related Compounds