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PLP(139-151)TFA

Names

[ CAS No. ]:
122018-58-0

[ Name ]:
PLP(139-151)TFA

[Synonym ]:
HSLGKWLGHPDKF
139-151 amino acid peptide of proteolipid protein
139-151 PLP
HIS-SER-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE
H2N-HSLGKWLGHPDKF-OH
PROTEOLIPID PROTEIN
PLP 139-151
HIS-SER-LEU-GLY-LYS-TRP-LEU-GLY-HLS-PRO-ASP-LYS-PHE
PLP(139-151)

Biological Activity

[Description]:

PLP(139-151) is a fragment of myelin proteolipid protein, induce experimental autoimmune encephalomyelitis (EAE).

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Peptides

[In Vitro]

The residues 144 and 147 of PLP(139-151) are recognized by T cell receptor (TCR) during the formation of trimolecular complex with peptide-antigen and major histocompability complex[1].

[References]

[1]. Kordopati GG, et al. Biologically relevant conformational features of linear and cyclic proteolipid protein (PLP) peptide analogues obtained by high-resolution nuclear magnetic resonance and molecular dynamics. J Comput Aided Mol Des. 2017 Jul 29.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C72H104N20O17

[ Molecular Weight ]:
1521.72000

[ Exact Mass ]:
1520.79000

[ PSA ]:
586.45000

[ LogP ]:
3.03910

[ Storage condition ]:
-20°C

Related Compounds