cIAP1 Ligand-Linker Conjugates 15

Names

[ CAS No. ]:
1225433-96-4

[ Name ]:
cIAP1 Ligand-Linker Conjugates 15

Biological Activity

[Description]:

E3 ligase Ligand-Linker Conjugates 34 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 34 can be used to design PROTAC degrader[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

cIAP1


[References]

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Chemical & Physical Properties

[ Molecular Formula ]:
C37H47N3O8

[ Molecular Weight ]:
661.78

Related Compounds