Fenbendazole-d3

Names

[ Name ]:
Fenbendazole-d3

[Synonym ]:
Axilur-d3
2-[(Methoxy-d3)carbonylamino]-5-(phenylthio)benzimidazole
Fenbendazole-d3
HOE 881-d3
Methyl-d3 5-(phenylthio)-2-benzimidazolecarbamate
Safe-Guard-d3
Fenbendazol-d3
Panacur-d3
Fenbion-d3

Biological Activity

[Description]:

Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole is a benzimidazole anthelmintic. Fenbendazole is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection. Fenbendazole also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

Chemical & Physical Properties

[ Boiling Point ]:
209-216 °C

[ Molecular Formula ]:
C₁₅H₁₀D₃N₃O₂S

[ Molecular Weight ]:
302.36600

[ Exact Mass ]:
302.09200

[ PSA ]:
95.80000

[ LogP ]:
3.90600

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport