3',5'-Difluoroacetophenone
Names
[ CAS No. ]:
123577-99-1
[ Name ]:
3',5'-Difluoroacetophenone
[Synonym ]:
1-(3,5-Difluorophenyl)-1-ethanone
1-(3,5-Difluorophenyl)ethan-1-one
1-Acetyl-3,5-difluorobenzene
3‘,5‘-Difluoroacetophenone
Ethanone, 1-(3,5-difluorophenyl)-
1-(3,5-Difluorophenyl)ethanone
3′,5′-Difluoroacetophenone
FR CF EV1
3,5-Difluoroacetophenone
3',5'-Difluoroacetophenone
MFCD00042489
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
190.7±20.0 °C at 760 mmHg
[ Melting Point ]:
34-38 °C(lit.)
[ Molecular Formula ]:
C8H6F2O
[ Molecular Weight ]:
156.129
[ Flash Point ]:
70.3±15.9 °C
[ Exact Mass ]:
156.038666
[ PSA ]:
17.07000
[ LogP ]:
1.91
[ Vapour Pressure ]:
0.5±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.473
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
Org. Biomol. Chem. 8(2) , 363-70, (2010)
We have prepared and characterized a Cu(i)-responsive fluorescent probe, constructed using a large tetradentate, 16-membered thiazacrown ligand ([16]aneNS(3)) and 1,3,5-triaryl-substituted pyrazoline ...
Synthesis of fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines.Bioorg. Med. Chem. Lett. 13(10) , 1725-8, (2003)
The synthesis of four (+/-)-fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines and an enantioselective approach to these amines through reductive amination are described.
(E)-1-(3, 5-Difluorophenyl)-3-(2, 4-dimethoxyphenyl) prop-2-en-1-one. Huang T, et al.Acta Crystallogr. Sect. E Struct. Rep. Online 66(10) , o2518-o2518, (2010)