SX-576
Names
[ CAS No. ]:
1240494-14-7
[ Name ]:
SX-576
Biological Activity
[Description]:
A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.
[References]
References 1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4. 2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. View Related Products by Target Chemokine Receptor (CCR and CXCR)
Chemical & Physical Properties
[ Molecular Formula ]:
C20H15BF4N2O4S
[ Molecular Weight ]:
466.214