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(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) trifluoroacetate salt

Names

[ CAS No. ]:
124199-90-2

[ Name ]:
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) trifluoroacetate salt

[Synonym ]:
h-d-phe-gln-trp-ala-val-gly-his-leu-nhet
D-Phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl-L-leucinamide
d-phe-gln-trp-ala-val-gly-his-leu-nhet
(d-phe6,leu-nhet13,des-met14)-bombesin (6-14)
L-Leucinamide, D-phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl-

Biological Activity

[Description]:

(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is a bombesin (BBN) antagonist and can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor

[References]

[1]. Podstawka E, et al. Potential-dependent studies on the interaction between phenylalanine-substituted bombesin fragments and roughened Ag, Au, and Cu electrode surfaces. J Phys Chem B. 2010 Jan 21;114(2):1010-29.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1489.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C49H69N13O9

[ Molecular Weight ]:
984.154

[ Flash Point ]:
854.7±34.3 °C

[ Exact Mass ]:
983.534119

[ PSA ]:
346.38000

[ LogP ]:
1.67

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.595

Related Compounds