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Ajugamarin L2

Names

[ CAS No. ]:
124961-67-7

[ Name ]:
Ajugamarin L2

[Synonym ]:
Ajugacumbin B
Ajugamarin L2

Biological Activity

[Description]:

Ajudecunoid A is nature product that could be isolated from Ajuga decumbens. Ajudecunoid A inhibits RANKL-Induced osteoclastogenesis[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Ajudecunoid A (compound 1; 3 and 10 μM; 48 h) 以浓度依赖性方式抑制 RANKL 诱导的破骨细胞生成[1]。 Cell Viability Assay[1] Cell Line: Osteoclastogenesis Concentration: 3 and 10 Μm Incubation Time: 48 hours Result: Inhibited RANKL-induced osteoclastogenesis in a concentration dependent manner.

[References]

[1]. Wang H, et, al. Diterpenoids from the Whole Plants of Ajuga nipponensis and Their Inhibition of RANKL-Induced Osteoclastogenesis. Chem Biodivers. 2021 Jan;18(1):e2000780.  

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
592ºC at 760 mmHg

[ Molecular Formula ]:
C25H36O6

[ Molecular Weight ]:
432.55000

[ Flash Point ]:
196.5ºC

[ Exact Mass ]:
432.25100

[ PSA ]:
85.36000

[ LogP ]:
3.72170

[ Vapour Pressure ]:
1.76E-16mmHg at 25°C

[ Index of Refraction ]:
1.553

[ Water Solubility ]:
Very slightly soluble (0.48 g/L) (25 ºC)


Related Compounds