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(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one

Names

[ CAS No. ]:
1251830-57-5

[ Name ]:
(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one

[Synonym ]:
(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one
6-Hepten-3-one, 1,7-bis(4-hydroxyphenyl)-, (6E)-

Biological Activity

[Description]:

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC50 value of 8.93 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Inflammation/Immunology

[References]

[1]. Li J, Zhao F, Li MZ, Chen LX, Qiu F. Diarylheptanoids from the Rhizomes of Curcuma kwangsiensis. J Nat Prod. 2010;73(10):1667-1671.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
539.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20O3

[ Molecular Weight ]:
296.36

[ Flash Point ]:
294.1±25.2 °C

[ Exact Mass ]:
296.141235

[ PSA ]:
57.53000

[ LogP ]:
3.05

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.627

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds