<Suppliers Price>

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

Names

[ CAS No. ]:
125678-68-4

[ Name ]:
Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

[Synonym ]:
N-Myristoyl-lysyl-arginyl-threonyl-leucyl-arginine
MYRISTOYL-KRTLR-OH
Mlatla
MYRISTOYL-KRTLR-OH INHIBITOR OF PKC
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
N-Myristyl-lys-arg-thr-leu-arg
N2-(N-(N-(N2-(N2-(1-Oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-L-arginine

Biological Activity

[Description]:

N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> PKC
Research Areas >> Inflammation/Immunology
Signaling Pathways >> TGF-beta/Smad >> PKC

[In Vitro]

N-Myristoyl-Lys-Arg-Thr-Leu-Arg (0-50 μM) inhibits the production and release of IL-2 from cultured Jurkat cells stimulated with TPA plus either PHA or OKT3 mAb[1].

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Molecular Formula ]:
C42H82N12O8

[ Molecular Weight ]:
883.17600

[ Exact Mass ]:
882.63800

[ PSA ]:
352.85000

[ LogP ]:
6.31520

[ Index of Refraction ]:
1.582

Related Compounds